Lisa Whalen

Lecturer III

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Chemical Education
Organic Chemistry

Contact Information

Email:
Phone: 505-277-0268
Fax: 505-277-2609
Office: Clark Hall Room 278
Website

Education

  • Ph.D. in Chemistry, 2004, University of Colorado-Boulder
  • Postdoctoral research associate, 2004-2006, The Scripps Research Institute

Research

  • Enzymes in organic synthesis and inhibition of carbohydrate-processing enzymes; protein binding and release from polyNIPAM surfaces.
  • Summer faculty at the Center for Integrated Nanotechnologies at Sandia.

Notes

Supervisor for Chemistry 303L and 304L

Selected Publications

  1. Sugiyama, M.; Hong, Z.; Liang, P.-H.; Dean, S.M.; Whalen, L.J.; Greenberg, W.A.; Wong, C.-H. D-Fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols. J. Am. Chem. Soc. 2007, 129, 14811.
  2. Whalen, L.J.; Greenberg, W.A.; Mitchell, M.L.; Wong, C.-H. Iminosugar-based glycosyltransferase inhibitors. In Iminosugars: From Synthesis to Therapeutic Applications, Chapter 7. Compain, P. and Martin, O., Eds. Chichester: Wiley VCH, 2007, p. 153-173.
  3. Yu, Z.; Sawkar, A.R.; Whalen, L.J.; Wong, C.-H.; Kelly, J.W. Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention. J. Med. Chem. 2007, 50, 94.
  4. Hanson, S.R.; Whalen, L.J.; Wong, C.-H. Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoromethyl)phenyl sulfate and cyclic phenyl sulfamate motifs. Bioorg. Med. Chem. 2006, 14(24), 8386.
  5. Sugiyama, M.; Hong, Z.; Whalen, L.J.; Greenberg, W.A.; Wong, C.-H. Borate as a phosphate ester mimic in aldolase-catalyzed reactions: practical synthesis of L-fructose and L-iminocyclitols. Adv. Synth. Catal. 2006, 348, 2555.