Functionalization Based on Common Functional Groups

February 20, 2015

Guangbin Dong

C-H and C-C bonds are the most abundant bonds in majority of organic compounds. Selective functionalization of C-C and C-H bonds would lead to efficient synthesis but of significant challenges. We have been focusing on a "cut and sew" strategy to synthesize bridged and fused rings by utilizing metal-catalyzed C-C bond activation. We have also been working on a number of ketone and alcohol-based site-selective C-H functionalizations for preparing useful building blocks.