Debra Dunaway-Mariano
| Position: | Professor of Chemistry, Biochemistry |
|---|---|
| Email: | dd39@unm.edu |
| Phone: | 505.277.3383 |
| Fax: | 505.277.2609 |
| Office: | Room #372 |
| Homepage: | http://www.unm.edu/~dd39/ |
Education
- B.S. in Chemistry, 1973, Texas A&M University
- Ph.D. in Chemistry, 1975, Texas A&M University
Research
The Dunaway-Mariano research program offers training at the interface of Organic, Physical and Biological Chemistry. Research projects target challenges in Medicine and Energy. For more information check out the web site: http://www.unm.edu/~dd39/ or contact Professor Dunaway-Mariano directly by email: dd39@unm.edu. Her research interests include:
- Synthesis of Medicinally Important Natural Products using Natural Catalysts
- Mechanisms of Catalysis of Environmental Friendly Chemistry
- Drug Discovery Through Rational Design and High Through-put Screening
- Conversion of Cellulose to Gasoline using Designer Natural Catalysts
Recent Publications
- Lu Z, Dunaway-Mariano D, Allen KN. The catalytic scaffold of the haloalkanoic acid dehalogenase enzyme superfamily acts as a mold for the trigonal bipyramidal transition state. Proc Natl Acad Sci U S A. 2008 105,5687-92.
- Li L, Li Z, Wang C, Xu D, Mariano PS, Guo H, Dunaway-Mariano D. The Electrostatic Driving Force for Nucleophilic Catalysis in l-Arginine Deiminase: A Combined Experimental and Theoretical Study. Biochemistry. 2008 Mar 27.
- Willis MA, Zhuang Z, Song F, Howard A, Dunaway-Mariano D, Herzberg O.Structure of YciA from Haemophilus influenzae (HI0827), a hexameric broad specificity acyl-coenzyme A thioesterase. Biochemistry (2008) 47, 2797-805.
- Zhuang Z, Song F, Zhao H, Li L, Cao J, Eisenstein E, Herzberg O, Dunaway-Mariano D.Divergence of function in the hot dog fold enzyme superfamily: the bacterial thioesterase YciA. Biochemistry. (2008) 47, 2789-96.
- Li L, Li Z, Chen D, Lu X, Feng X, Wright EC, Solberg NO, Dunaway-Mariano D, Mariano PS, Galkin A, Kulakova L, Herzberg O, Green-Church KB, Zhang L. Inactivation of microbial arginine deiminases by L-canavanine.J Am Chem Soc. (2008) 130, 1918-31.